What are the macrophages in the liver called?

• A. Hepatocytes
• B. Kupffer cells
• C. Islet cells
• D. Osteoclasts

Answer: (B)

The liver’s resident macrophages are Kupffer cells. They line the hepatic sinusoids and are part of the reticuloendothelial system, constantly patrolling portal blood from the gut to phagocytose bacteria, debris, and aged red blood cells. They also secrete cytokines and can present antigens to help coordinate immune responses. Hepatocytes are the main metabolic liver cells, islet cells are pancreatic endocrine cells, and osteoclasts resorb bone. Kupffer cells are the macrophages specifically in the liver.